SCHEMBL28023181

SCHEMBL28023181

CCCCc1cccc(C=O)c1Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
CYSLTR2 Q9NS75 1/20 0.37
CYSLTR1 Q9Y271 1/20 0.37
TLR8 Q9NR97 1/20 0.37
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27464370 0.85 LIPG (0.40) LIPGCYSLTR2CYSLTR1BIDMCL1
SCHEMBL8087736 0.85 TLR8 (0.43) LIPGSIGMAR1CYSLTR2CYSLTR1TLR8
SCHEMBL29153432 0.82 MEN1 (0.44) BCL2L1CYP3A4CYP2D6CYP2C9HPGD
SCHEMBL8670404 0.81 CYSLTR2 (0.41) CYSLTR2CYSLTR1TLR8BIDMCL1
SCHEMBL8099594 0.80 LIPG (0.49) LIPGSIGMAR1TLR8BIDMCL1
SCHEMBL266417 0.80 LIPG (0.47) LIPGTLR8CYP3A4CYP2D6CYP2C9
SCHEMBL9721777 0.80 KCNH2 (0.46) LIPGSIGMAR1CYSLTR2CYSLTR1BID
SCHEMBL28690662 0.80 LIPG (0.49) LIPGCYSLTR2CYSLTR1BIDMCL1
SCHEMBL28861107 0.80 LIPG (0.49) LIPGCYSLTR2CYSLTR1BIDMCL1
SCHEMBL8095518 0.79 TLR8 (0.44) LIPGSIGMAR1CYSLTR2CYSLTR1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105496904-A Toning lotion for hypersensitive skin WANG JINGYI 2016-04-20 CN claimed
CN-104887590-A Deep cleansing cream ZHOU DONG 2015-09-09 CN claimed
CN-105496904-A Toning lotion for hypersensitive skin WANG JINGYI 2016-04-20 CN disclosed
CN-104887590-A Deep cleansing cream ZHOU DONG 2015-09-09 CN disclosed