Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087736 | 0.88 | TLR8 (0.43) | CYSLTR2CYSLTR1TLR8BIDMCL1 | |
| SCHEMBL8099594 | 0.83 | LIPG (0.49) | TLR8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL1005447 | 0.83 | BID (0.40) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL8096674 | 0.81 | LIPG (0.51) | CYSLTR2CYSLTR1TLR8BIDMCL1 | |
| SCHEMBL8101482 | 0.81 | LIPG (0.51) | CYSLTR2CYSLTR1TLR8BIDMCL1 | |
| SCHEMBL8095518 | 0.81 | TLR8 (0.44) | CYSLTR2CYSLTR1TLR8LMNAHTT | |
| SCHEMBL8095441 | 0.81 | LIPG (0.51) | CYSLTR2CYSLTR1TLR8BIDMCL1 | |
| SCHEMBL28023181 | 0.81 | LIPG (0.38) | CYSLTR2CYSLTR1TLR8BIDMCL1 | |
| SCHEMBL11237338 | 0.81 | SIGMAR1 (0.40) | CYSLTR2CYSLTR1TLR8LMNAHTT | |
| SCHEMBL9845811 | 0.81 | HSP90AA1 (0.49) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |