Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907349 | 0.78 | HTT (0.53) | KMT2AHTTALDH1A1HRH3MAP4K4 | |
| SCHEMBL15442302 | 0.78 | HPGD (0.47) | KMT2AALDH1A1HPGDRXRARXRB | |
| SCHEMBL510046 | 0.77 | LTA4H (0.58) | HTTALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL17050832 | 0.76 | ACACB (0.57) | KMT2A | |
| SCHEMBL23720010 | 0.76 | KMT2A (0.66) | KMT2AHTTALDH1A1HRH3MAP4K4 | |
| SCHEMBL31683886 | 0.76 | KMT2A (0.66) | KMT2AHTTALDH1A1HRH3MAP4K4 | |
| SCHEMBL28714581 | 0.76 | KMT2A (0.60) | KMT2AHTTALDH1A1HRH3MAP4K4 | |
| SCHEMBL29479486 | 0.76 | KMT2A (0.60) | KMT2AHTTALDH1A1HRH3MAP4K4 | |
| SCHEMBL30700673 | 0.76 | KMT2A (0.60) | KMT2AHTTALDH1A1HRH3MAP4K4 | |
| SCHEMBL21902104 | 0.75 | KMT2A (0.56) | KMT2AHTTALDH1A1HRH3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684900-A | Substituted pyrimidine compound and uses thereof | SINOCHEM CORP | 2015-06-03 | — | — | CN | disclosed |