Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479486 | 1.00 | KMT2A (0.60) | KMT2AALDH1A1HTTMAP4K4HRH3 | |
| SCHEMBL28714581 | 1.00 | KMT2A (0.60) | KMT2AALDH1A1HTTMAP4K4HRH3 | |
| SCHEMBL30835340 | 0.88 | KMT2A (0.48) | KMT2AALDH1A1HTTMAP4K4HRH3 | |
| SCHEMBL27083288 | 0.88 | KMT2A (0.48) | KMT2AALDH1A1HTTMAP4K4HRH3 | |
| SCHEMBL23720010 | 0.79 | KMT2A (0.66) | KMT2AALDH1A1HTTMAP4K4HRH3 | |
| SCHEMBL31683886 | 0.79 | KMT2A (0.66) | KMT2AALDH1A1HTTMAP4K4HRH3 | |
| SCHEMBL510244 | 0.79 | KMT2A (0.66) | KMT2AALDH1A1HTTMAP4K4MEN1 | |
| SCHEMBL17050816 | 0.79 | L3MBTL1 (0.42) | KMT2AALDH1A1HTTMEN1OXTR | |
| SCHEMBL17050464 | 0.78 | SMN1; SMN2 (0.43) | KMT2AALDH1A1MEN1LMNAL3MBTL1 | |
| SCHEMBL17050451 | 0.78 | L3MBTL1 (0.41) | KMT2AALDH1A1HTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |