Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 7/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023310 | 0.87 | KDM4E (0.54) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL3888738 | 0.81 | AR (0.59) | LMNAARMAPTALDH1A1KDM4E | |
| SCHEMBL8387303 | 0.77 | KDM4E (0.59) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL3555503 | 0.76 | AR (0.58) | LMNAARMAPTALDH1A1POLB | |
| SCHEMBL28023857 | 0.74 | MEN1 (0.55) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL6045360 | 0.74 | KDM4E (0.62) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL30804630 | 0.74 | KDM4E (0.62) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL28023305 | 0.74 | KIF11 (0.53) | MAPTALDH1A1KDM4ESMN1; SMN2MEN1 | |
| Benzene SCHEMBL30804625 | 0.73 | KDM4E (0.60) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL7637488 | 0.73 | MAPT (0.59) | ARMAPTNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744340-A | Polysubstituted carbazole compound, preparation method and application thereof | PEOPLES UNIV CHINA | 2015-07-01 | — | — | CN | disclosed |