Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804630 | 1.00 | KDM4E (0.62) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| Benzene SCHEMBL30804625 | 0.99 | KDM4E (0.60) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8387303 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11737708 | 0.84 | CLEC4M (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15709468 | 0.83 | ERAP1 (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9485757 | 0.83 | MPL (0.61) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11809823 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3105919 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RAB9AKMT2ATSHRDHFR | |
| SCHEMBL479247 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28023310 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486990-B2 | SirT inhibitors that bind to NAD | ELIXIR PHARMACEUTICALS, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20060074124-A1 | Methods of treating a disorder | IPSOL AG (LI) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074124-A1 | Methods of treating a disorder | CPT1B, CYP27A1, CLN6 | KDM4E 3776/4885ALDH1A1 418/4885MAPT 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.