SCHEMBL28023319

SCHEMBL28023319

CCC(c1cccc(N=C=O)c1N=C=O)c1cccc(N=C=O)c1N=C=O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.49
GABRB2 P47870 2/20 0.49
CYP3A4 P08684 3/20 0.47
TRPA1 O75762 1/20 0.32
TSHR P16473 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11445026 0.84 CYP3A4 (0.47) GABRA1GABRB2CYP3A4TRPA1TSHR
SCHEMBL112144 0.81 CYP3A4 (0.52) GABRA1GABRB2CYP3A4TRPA1TSHR
SCHEMBL28036817 0.77 CYP3A4 (0.43) GABRA1GABRB2CYP3A4ALDH1A1TDP1
SCHEMBL3440189 0.75 CYP3A4 (0.50) GABRA1GABRB2CYP3A4TRPA1
SCHEMBL109280 0.75 CYP3A4 (0.62) GABRA1GABRB2CYP3A4TRPA1TSHR
SCHEMBL109349 0.75 GABRA1 (0.78) GABRA1GABRB2CYP3A4TRPA1TSHR
SCHEMBL11761663 0.74 CYP3A4 (0.41) GABRA1GABRB2CYP3A4TSHR
SCHEMBL9623452 0.74 GABRA1 (0.53) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL28611992 0.74 CYP3A4 (0.47) GABRA1GABRB2CYP3A4TRPA1TSHR
SCHEMBL2170759 0.73 GABRA1 (0.49) GABRA1GABRB2CYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109312166-A Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal indicate element 日产化学株式会社 2019-02-05 CN disclosed
CN-105518521-A Polymer composition and liquid crystal alignment film for in-plane switching liquid crystal display element NISSAN CHEMICAL IND LTD 2016-04-20 CN disclosed
CN-105122128-A Production method for liquid-crystal alignment film, liquid-crystal alignment film, liquid-crystal display element, and liquid-crystal alignment agent NISSAN CHEMICAL IND LTD 2015-12-02 CN disclosed