Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | MAP2 | P11137 | 1/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023856 | 0.85 | WEE1 (0.50) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL28023304 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDPIM1MAPT | |
| SCHEMBL28181009 | 0.84 | PIM3 (0.59) | ALDH1A1KDM4EHPGDMAP2MPL | |
| SCHEMBL4866489 | 0.84 | MPL (0.48) | KDM4EPARP14MPLPIM3PIM1 | |
| SCHEMBL28241456 | 0.82 | PARP14 (0.47) | ALDH1A1KDM4EHPGDPARP14MAP2 | |
| SCHEMBL31485136 | 0.80 | PBRM1 (0.58) | PARP14MPLPIM3PIM1MAPT | |
| SCHEMBL3910030 | 0.80 | PBRM1 (0.58) | PARP14MPLPIM3PIM1MAPT | |
| SCHEMBL28876094 | 0.78 | PARP14 (0.57) | PARP14PBRM1 | |
| SCHEMBL28023310 | 0.78 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTGAA | |
| Benzophenone SCHEMBL28907230 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744340-B | Polysubstituted carbazole compound and preparation method and application | 中国人民大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-104744340-A | Polysubstituted carbazole compound, preparation method and application thereof | PEOPLES UNIV CHINA | 2015-07-01 | — | — | CN | disclosed |