SCHEMBL4866489

SCHEMBL4866489

O=C(c1ccccc1)c1ccc2c([nH]c3ccccc32)c1C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 2/20 0.48
PIM3 Q86V86 2/20 0.48
PIM1 P11309 1/20 0.48
PARP14 Q460N5 1/20 0.47
APP P05067 1/20 0.46
KIF11 P52732 2/20 0.45
PBRM1 Q86U86 1/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
GABRA4 P48169 1/20 0.44
GABRE P78334 1/20 0.44
GABRA6 Q16445 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3910030 0.84 PBRM1 (0.58) MPLPIM3PIM1PARP14APP
SCHEMBL31485136 0.84 PBRM1 (0.58) MPLPIM3PIM1PARP14APP
SCHEMBL28023323 0.84 ALDH1A1 (0.48) MPLPIM3PIM1PARP14KIF11
SCHEMBL28183918 0.83 KIF11 (0.51) MPLPIM3PIM1PARP14APP
SCHEMBL29516203 0.81 MPL (0.57) MPLPIM3PIM1PARP14APP
SCHEMBL87518 0.81 MPL (0.57) MPLPIM3PIM1PARP14APP
SCHEMBL27695927 0.79 PARP14 (0.61) PARP14PBRM1
SCHEMBL6887283 0.79 PBRM1 (0.55) MPLPIM3PIM1PARP14KIF11
Carbazole SCHEMBL28977818 0.78 PARP14 (0.60) PARP14PBRM1
Benzophenone SCHEMBL27485001 0.77 ALDH1A1 (0.61) KIF11GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7455887-B2 Actinic ray curable ink-jet ink composition, image formation method employing the same, and ink-jet recording apparatus KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2008-11-25 US disclosed
US-20050113483-A1 Actinic ray curable ink-jet ink composition, image formation method employing the same, and ink-jet recording apparatus KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-05-26 US disclosed