Methacrylic Acid

Methacrylic Acid

SCHEMBL28023766

C=C.C=C(C)C(=O)O.C=CC(=O)OC

nearest known ligand 0.42

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.42
HCAR2 Q8TDS4 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.35
TSHR P16473 8/20 0.34
TP53 P04637 3/20 0.33
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 3/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28132307 1.00 ALDH1A1 (0.42) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL261881 0.98 ALDH1A1 (0.44) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL27673675 0.98 ALDH1A1 (0.44) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL28331486 0.94 ALDH1A1 (0.38) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL27757757 0.93 ALDH1A1 (0.41) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL28076071 0.93 LMNA (0.43) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL28239726 0.91 ALDH1A1 (0.39) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL28213346 0.91 ALDH1A1 (0.39) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL28160339 0.91 ALDH1A1 (0.39) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10
Methacrylic Acid SCHEMBL28185913 0.91 ALDH1A1 (0.39) ALDH1A1HCAR2KEAP1NFE2L2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106003943-A Three-layer co-extrusion biodegradable mulch film and preparation method thereof 深圳市虹彩新材料科技有限公司 2016-10-12 CN claimed
CN-107011654-A A kind of halogen-free flameproof enhancing PA6/PBT alloys and preparation method thereof 武汉理工大学 2017-08-04 CN disclosed
CN-106003943-A Three-layer co-extrusion biodegradable mulch film and preparation method thereof 深圳市虹彩新材料科技有限公司 2016-10-12 CN disclosed
CN-104672898-A Highlight anti-warping reinforced nylon PA66 SUZHOU WEIRUICHENG NEW MATERIAL CO LTD 2015-06-03 CN disclosed