SCHEMBL28023787

SCHEMBL28023787

O=C(Nc1ncnc2c1ncn2[C@]1(C2O[C@H](CO)[C@@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 4/20 0.48
SLC29A1 Q99808 2/20 0.48
TP53 P04637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ADORA1 P30542 7/20 0.48
ADORA2A P29274 3/20 0.47
ADORA2B P29275 2/20 0.47
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.47
NFKB1 P19838 2/20 0.47
THPO P40225 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
PMP22 Q01453 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPC1 O15118 1/20 0.47
NPY1R P25929 1/20 0.47
HTT P42858 1/20 0.47
NPY2R P49146 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6908906 0.89 ADORA1 (0.41) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL31677375 0.89 ADORA1 (0.41) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL28165438 0.83 ADORA1 (0.45) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL7774654 0.82 ADORA1 (0.39) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL27518665 0.82 ADORA1 (0.43) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL19485512 0.80 LMNA (0.72) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL313413 0.80 LMNA (0.72) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL9945526 0.80 LMNA (0.72) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL6909853 0.80 LMNA (0.72) ADORA3SLC29A1TP53TDP1ADORA1
SCHEMBL21953578 0.80 LMNA (0.72) ADORA3SLC29A1TP53TDP1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104968669-B Synthesis of deuterated ribonucleosides, N-protected phosphoramidites and oligonucleotides 阿萨德有限公司 2019-03-22 CN disclosed
CN-104968669-A Synthesis of deuterated ribonucleosides, N-protected phosphoramidites and oligonucleotides ASED LLC 2015-10-07 CN disclosed
CN-104812770-A Synthesis of deuterated ribonucleosides, N-protected phosphoramidites and oligonucleotides ASED LLC 2015-07-29 CN disclosed