⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15155212 | 1.00 | — | — | |
| SCHEMBL21634967 | 0.87 | THRB (0.43) | — | |
| SCHEMBL158888 | 0.80 | — | — | |
| SCHEMBL28338693 | 0.80 | THRB (0.37) | — | |
| SCHEMBL20377439 | 0.79 | ALOX15 (0.46) | — | |
| SCHEMBL1988197 | 0.79 | — | — | |
| Glutamine SCHEMBL28491842 | 0.78 | KMT2A (0.76) | — | |
| Glutamine SCHEMBL8037581 | 0.78 | KMT2A (0.76) | — | |
| Glycerin SCHEMBL8015455 | 0.78 | DPP4 (0.39) | — | |
| SCHEMBL1747943 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-110256418-A | The benzamide that 1,3- thiazol-2-yl replaces | 拜耳公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-107207507-A | 1, 3-thiazol-2-yl substituted benzamides | 拜耳公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-104812753-A | Substituted pyridopyrazines as syk inhibitors | HUTCHISON MEDIPHARMA LTD | 2015-07-29 | — | — | CN | disclosed |