Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612612 | 0.92 | MAPT (0.42) | NPSR1MAPTCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL12467413 | 0.83 | NPSR1 (0.38) | NPSR1MAPTCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL27032847 | 0.79 | TSHR (0.43) | CYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL20314661 | 0.78 | KMT2A (0.36) | EPHX1KMT2AMEN1 | |
| SCHEMBL25866514 | 0.76 | CYP1A2 (0.43) | — | |
| SCHEMBL23374704 | 0.75 | MAPT (0.41) | NPSR1MAPTCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL9781676 | 0.75 | NPSR1 (0.35) | NPSR1MAPTCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL5926960 | 0.75 | GNAI3 (0.42) | EPHX1KMT2A | |
| SCHEMBL5524661 | 0.73 | MAPT (0.47) | NPSR1MAPTCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL9781658 | 0.73 | CYP4F2 (0.36) | NPSR1MAPTCYP4F2CYP4A11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870007-A | New antiviral macrocycles | SCYNEXIS INC | 2015-08-26 | — | — | CN | disclosed |