SCHEMBL28023990

SCHEMBL28023990

COC(=O)C(C)(C)c1nc(C)c(C)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 1/20 0.38
PLCG1 P19174 1/20 0.35
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
BRS3 P32247 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
DGAT1 O75907 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
MAPT P10636 1/20 0.30
CRHBP P24387 1/20 0.30
MAPK1 P28482 1/20 0.30
CRHR2 Q13324 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3695099 0.69 L3MBTL1 (0.40) ALDH1A1L3MBTL1
SCHEMBL20470626 0.68 MAPT (0.41) KDM4EALDH1A1L3MBTL1LMNAHTT
SCHEMBL15690079 0.66 NPSR1 (0.43) SMPD3KDM4EALDH1A1LMNAHTT
SCHEMBL17544703 0.64 ALDH1A1 (0.41) SMPD3PLCG1KDM4EALDH1A1LMNA
SCHEMBL16660737 0.63
SCHEMBL13721978 0.62 SMN1; SMN2 (0.38) SMPD3KDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL19779527 0.60 CNR1 (0.41) PLCG1LMNABRS3CNR1CNR2
SCHEMBL31292151 0.60 KDM4E (0.38) PLCG1KDM4EALDH1A1L3MBTL1BRS3
SCHEMBL31292565 0.60 KMT2A (0.35) PLCG1KDM4EALDH1A1LMNABRS3
SCHEMBL20910181 0.60 MEN1 (0.48) PLCG1KDM4EALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104903375-A CATALYSTS FOR POLYURETHANE COATING COMPOUNDS BASF SE 2015-09-09 CN disclosed