⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372723 | 0.97 | TSHR (0.38) | — | |
| SCHEMBL27414429 | 0.97 | TSHR (0.38) | — | |
| SCHEMBL1829807 | 0.97 | TSHR (0.38) | — | |
| Hydrochloric Acid SCHEMBL1372820 | 0.94 | TSHR (0.41) | — | |
| Hydrochloric Acid SCHEMBL8741359 | 0.94 | TSHR (0.41) | — | |
| SCHEMBL1794983 | 0.94 | — | — | |
| SCHEMBL5438837 | 0.92 | ALDH1A1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL15772686 | 0.91 | — | — | |
| SCHEMBL5431132 | 0.89 | ALDH1A1 (0.38) | — | |
| SCHEMBL503843 | 0.88 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4298095-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | Sperogenix Therapeutics Limited (HK) | 2024-01-03 | — | — | EP | claimed |
| WO-2022162606-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | SPEROGENIX THERAPEUTICS LIMITED (CN) | 2022-08-04 | — | — | WO | claimed |
| EP-4010335-A1 | SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2022-06-15 | — | — | EP | claimed |
| WO-2021028362-A1 | SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2021-02-18 | — | — | WO | claimed |
| EP-2822941-A1 | BENZODIOXANES IN COMBINATION WITH OTHER ACTIVES FOR INHIBITING LEUKOTRIENE PRODUCTION | Boehringer Ingelheim International GmbH (DE) | 2015-01-14 | — | — | EP | claimed |
| WO-2013131901-A1 | BENZODIOXANES IN COMBINATION WITH OTHER ACTIVES FOR INHIBITING LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-12 | — | — | WO | claimed |
| JP-4749715-B2 | — | — | 2011-08-17 | — | — | JP | claimed |
| JP-2011509933-A | — | — | 2011-03-31 | — | — | JP | claimed |
| EP-2242364-A1 | PREPARATION AND ENANTIOMERIC SEPARATION OF 7-(3-PYRIDINYL)-1,7-DIAZASPIROÝ4.4¨NONANE AND NOVEL SALT FORMS OF THE RACEMATE AND ENANTIOMERS | Targacept Inc. (US) | 2010-10-27 | — | — | EP | claimed |
| WO-2009091561-A1 | PREPARATION AND ENANTIOMERIC SEPARATION OF 7-(3-PYRIDINYL)-1,7-DIAZASPIRO[4.4] NONANE AND NOVEL SALT FORMS OF THE RACEMATE AND ENANTIOMERS | TARGACEPT, INC. (US) | 2009-07-23 | — | — | WO | claimed |
| EP-0307872-A2 | Esters of amino-acids, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | claimed |
| EP-0265685-A2 | Combination of ACE inhibitors with calcium antagonists, and their use in medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-04 | — | — | EP | claimed |
| EP-0243645-A2 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | claimed |
| EP-0126986-B1 | PROCESS FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-05 | — | — | EP | claimed |
| EP-0219782-A2 | Use of angiotensin-converting enzyme inhibitors in the treatment of atherosclerosis, thrombosis and peripheral vascular disease | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-29 | — | — | EP | claimed |
| EP-0158157-A1 | Method for the treatment of glaucoma | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-16 | — | — | EP | claimed |
| US-4525301-A | REACTING TRIFLUOROMETHANE SULFONIC ACID DERIVATIVES WITH AMINO ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | claimed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | claimed |
| EP-0135181-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | claimed |
| EP-0126986-A1 | Process for producing N-alkylated dipeptides and their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-05 | — | — | EP | claimed |