Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15771953 | 0.87 | ALDH1A1 (0.73) | ALDH1A1LMNAHSD17B10MAPTGAA | |
| SCHEMBL3056465 | 0.84 | ALDH1A1 (0.69) | ALDH1A1LMNAHSD17B10MAPTGAA | |
| SCHEMBL15780652 | 0.81 | ALDH1A1 (0.75) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL5647976 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7266853 | 0.80 | ALDH1A1 (0.63) | ALDH1A1LMNAHSD17B10MAPTGAA | |
| SCHEMBL20946436 | 0.80 | ALDH1A1 (0.73) | ALDH1A1LMNAHSD17B10MAPTGAA | |
| SCHEMBL5649934 | 0.80 | NPSR1 (0.65) | ALDH1A1LMNAMAPTGAA | |
| SCHEMBL2934786 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAAHPGDCA1CA2 | |
| Bromide SCHEMBL15772330 | 0.79 | ALDH1A1 (0.71) | ALDH1A1LMNAHSD17B10MAPTGAA | |
| SCHEMBL5649086 | 0.79 | CA1 (0.60) | ALDH1A1LMNAMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903291-A | Benzyl sulfonamide derivatives as RORc modulators | HOFFMANN LA ROCHE | 2015-09-09 | — | — | CN | disclosed |