Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329695 | 0.86 | ALDH1A1 (0.57) | ALDH1A1UCHL1GAAKMT2AL3MBTL1 | |
| SCHEMBL13840386 | 0.86 | ALDH1A1 (0.58) | ALDH1A1UCHL1GAAKMT2AL3MBTL1 | |
| SCHEMBL20946436 | 0.84 | ALDH1A1 (0.73) | ALDH1A1GAACA2CA1GBA1 | |
| SCHEMBL15771953 | 0.84 | ALDH1A1 (0.73) | ALDH1A1GAAKMT2ACA2CA1 | |
| Bromide SCHEMBL15772330 | 0.83 | ALDH1A1 (0.71) | ALDH1A1GAACA2CA1GBA1 | |
| SCHEMBL7862567 | 0.81 | GBA1 (0.74) | ALDH1A1GAAKMT2AL3MBTL1CA2 | |
| SCHEMBL3056465 | 0.81 | ALDH1A1 (0.69) | ALDH1A1GAAKMT2ACA2CA1 | |
| SCHEMBL28024040 | 0.81 | ALDH1A1 (0.69) | ALDH1A1GAAKMT2ACA2CA1 | |
| SCHEMBL12181468 | 0.81 | ALDH1A1 (0.68) | ALDH1A1UCHL1KMT2AL3MBTL1CA2 | |
| SCHEMBL21480862 | 0.80 | ALDH1A1 (0.54) | ALDH1A1GAAKMT2AGBA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382222-B2 | Benzyl sulfonamide derivatives as RORc modulators | GENENTECH, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20140163024-A1 | BENZYL SULFONAMIDE DERIVATIVES AS RORc MODULATORS | GENENTECH, INC. (US) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163024-A1 | BENZYL SULFONAMIDE DERIVATIVES AS RORc MODULATORS | RORC, RORA, RORB | ALDH1A1 1145/4885UCHL1 4129/4885GAA 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.