Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024498 | 0.94 | MRGPRX4 (0.40) | MRGPRX4HIF1APPARAPPARGPPARD | |
| SCHEMBL28024501 | 0.92 | MRGPRX4 (0.42) | MRGPRX4HIF1ANR1H4 | |
| SCHEMBL28024071 | 0.91 | MRGPRX4 (0.38) | MRGPRX4HIF1APPARAPPARGCYP2C9 | |
| SCHEMBL28024488 | 0.90 | HIF1A (0.38) | MRGPRX4HIF1APPARAPPARGNR1H4 | |
| SCHEMBL28024520 | 0.90 | MRGPRX4 (0.44) | MRGPRX4PPARAPPARGPPARDNR1H4 | |
| SCHEMBL28024064 | 0.90 | MRGPRX4 (0.41) | MRGPRX4HIF1ANR1H4RXRARXRB | |
| SCHEMBL28024479 | 0.90 | HIF1A (0.43) | MRGPRX4HIF1APPARAPPARGPPARD | |
| SCHEMBL28024039 | 0.89 | MRGPRX4 (0.42) | MRGPRX4HIF1APPARACYP2C9RXRA | |
| SCHEMBL28024545 | 0.89 | ALDH1A1 (0.39) | — | |
| SCHEMBL28097578 | 0.89 | NR1H4 (0.42) | MRGPRX4HIF1APPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |