Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024064 | 0.90 | MRGPRX4 (0.41) | MRGPRX4FFAR1FFAR4NR1H4PTGER1 | |
| SCHEMBL28024044 | 0.90 | MRGPRX4 (0.41) | MRGPRX4NR1H4PPARGPPARDPPARA | |
| SCHEMBL28024498 | 0.89 | MRGPRX4 (0.40) | MRGPRX4NR1H4PPARGPPARDPPARA | |
| SCHEMBL28024501 | 0.87 | MRGPRX4 (0.42) | MRGPRX4FFAR1FFAR4NR1H4 | |
| SCHEMBL28024479 | 0.85 | HIF1A (0.43) | MRGPRX4PPARGPPARDPPARARXRA | |
| SCHEMBL28097578 | 0.84 | NR1H4 (0.42) | MRGPRX4NR1H4PPARGPPARDPPARA | |
| SCHEMBL28024071 | 0.81 | MRGPRX4 (0.38) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL28024488 | 0.80 | HIF1A (0.38) | MRGPRX4NR1H4PPARGPPARAPTGER1 | |
| SCHEMBL28024039 | 0.79 | MRGPRX4 (0.42) | MRGPRX4PPARAPTGER1RXRARXRB | |
| SCHEMBL28024545 | 0.79 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |