Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024039 | 0.91 | MRGPRX4 (0.42) | CYP2C9HIF1AMRGPRX4 | |
| SCHEMBL28024473 | 0.90 | MRGPRX4 (0.45) | CYP2C9HIF1AMRGPRX4NPC1RAB9A | |
| SCHEMBL28024500 | 0.89 | MRGPRX4 (0.46) | CYP2C9HIF1AMRGPRX4FFAR1FFAR4 | |
| SCHEMBL28097588 | 0.86 | MRGPRX4 (0.39) | CYP2C9HIF1AMRGPRX4RAB9A | |
| SCHEMBL28024044 | 0.85 | MRGPRX4 (0.41) | CYP2C9HIF1AMRGPRX4 | |
| SCHEMBL28024501 | 0.85 | MRGPRX4 (0.42) | HIF1AMRGPRX4TP53HTTFFAR1 | |
| SCHEMBL28821177 | 0.85 | MRGPRX4 (0.44) | MRGPRX4 | |
| SCHEMBL28024495 | 0.83 | MRGPRX4 (0.38) | CYP2C9HIF1AMRGPRX4 | |
| SCHEMBL28024050 | 0.81 | MRGPRX4 (0.46) | CYP2C9HIF1AMRGPRX4 | |
| SCHEMBL28821202 | 0.81 | MRGPRX4 (0.46) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |