Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821202 | 0.90 | MRGPRX4 (0.46) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL28024063 | 0.88 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRGCYP2C9 | |
| SCHEMBL28024548 | 0.88 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL28024039 | 0.87 | MRGPRX4 (0.42) | MRGPRX4RXRARXRBRXRGTSHR | |
| SCHEMBL28024078 | 0.85 | MRGPRX4 (0.44) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL28024044 | 0.85 | MRGPRX4 (0.41) | MRGPRX4RXRARXRBRXRGCYP2C9 | |
| SCHEMBL28016556 | 0.85 | THRA (0.45) | MRGPRX4 | |
| SCHEMBL28016544 | 0.84 | MAPT (0.41) | MRGPRX4RXRARXRBRXRGLMNA | |
| SCHEMBL28024500 | 0.82 | MRGPRX4 (0.46) | MRGPRX4CYP2C9HIF1APPARAALDH1A1 | |
| SCHEMBL28097588 | 0.82 | MRGPRX4 (0.39) | MRGPRX4KDM4ECYP2C9HIF1APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |