Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097578 | 0.85 | NR1H4 (0.42) | HIF1AMRGPRX4NR1H4 | |
| SCHEMBL28024484 | 0.84 | MRGPRX4 (0.36) | HIF1AMRGPRX4NR1H4 | |
| SCHEMBL28024547 | 0.84 | MRGPRX4 (0.38) | HIF1AMRGPRX4NR1H4 | |
| SCHEMBL28020693 | 0.83 | MRGPRX4 (0.39) | MRGPRX4RAB9ASMN1; SMN2NPC1NR1H4 | |
| SCHEMBL28020690 | 0.78 | MRGPRX4 (0.38) | MRGPRX4NR1H4 | |
| SCHEMBL28020979 | 0.78 | NR1H4 (0.39) | MRGPRX4NR1H4 | |
| SCHEMBL28020975 | 0.78 | MRGPRX4 (0.41) | MRGPRX4NR1H4 | |
| SCHEMBL28016501 | 0.76 | MRGPRX4 (0.43) | HIF1AMRGPRX4 | |
| SCHEMBL28020688 | 0.76 | MRGPRX4 (0.37) | MRGPRX4NR1H4 | |
| SCHEMBL28024495 | 0.76 | MRGPRX4 (0.38) | HIF1AMRGPRX4MAPTL3MBTL1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |