Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821202 | 0.88 | MRGPRX4 (0.46) | MRGPRX4CREBBPAKR1B10AKR1B1AKR1C4 | |
| SCHEMBL28020693 | 0.80 | MRGPRX4 (0.39) | MRGPRX4 | |
| SCHEMBL28097578 | 0.79 | NR1H4 (0.42) | MRGPRX4PPARGPPARAHIF1A | |
| SCHEMBL28024050 | 0.78 | MRGPRX4 (0.46) | MRGPRX4PPARACYP2C9HIF1ATSHR | |
| SCHEMBL28024063 | 0.78 | MRGPRX4 (0.43) | MRGPRX4PPARACYP2C9HIF1A | |
| SCHEMBL28024548 | 0.78 | MRGPRX4 (0.43) | MRGPRX4 | |
| SCHEMBL28024495 | 0.77 | MRGPRX4 (0.38) | MRGPRX4PPARGPPARACYP2C9HIF1A | |
| SCHEMBL28024044 | 0.77 | MRGPRX4 (0.41) | MRGPRX4PPARGPPARACYP2C9HIF1A | |
| SCHEMBL28825838 | 0.77 | HTT (0.45) | MRGPRX4PPARACYP2C9HIF1ATSHR | |
| SCHEMBL28048671 | 0.76 | MRGPRX4 (0.46) | MRGPRX4CREBBPCYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |
| CN-104684908-A | Tetrazolinone compounds and their use as pesticides | SUMITOMO CHEMICAL CO | 2015-06-03 | — | — | CN | disclosed |