Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097578 | 0.90 | NR1H4 (0.42) | MRGPRX4NR1H4HIF1A | |
| SCHEMBL28024039 | 0.89 | MRGPRX4 (0.42) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28024484 | 0.89 | MRGPRX4 (0.36) | MRGPRX4NR1H4CYP2C9HIF1A | |
| SCHEMBL28020693 | 0.85 | MRGPRX4 (0.39) | MRGPRX4NR1H4 | |
| SCHEMBL28024059 | 0.84 | HIF1A (0.38) | MRGPRX4NR1H4HIF1A | |
| SCHEMBL28024473 | 0.84 | MRGPRX4 (0.45) | MRGPRX4CYP2C9HIF1A | |
| SCHEMBL28024500 | 0.83 | MRGPRX4 (0.46) | MRGPRX4CYP2C9HIF1A | |
| SCHEMBL28097588 | 0.83 | MRGPRX4 (0.39) | MRGPRX4CYP2C9HIF1A | |
| SCHEMBL28821177 | 0.82 | MRGPRX4 (0.44) | MRGPRX4 | |
| SCHEMBL28024045 | 0.81 | CYP2C9 (0.40) | MRGPRX4CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |