Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135872 | 0.96 | IKBKB (0.54) | IKBKBTLR8GABRPGABRDGABRA1 | |
| SCHEMBL19841045 | 0.87 | TLR8 (0.49) | IKBKBTLR8GABRPGABRDGABRA1 | |
| SCHEMBL570984 | 0.77 | TLR8 (0.54) | TLR8TRPV1CYP3A4MAPTALDH1A1 | |
| SCHEMBL28146814 | 0.77 | TLR8 (0.62) | TLR8TRPV1MAPTKMT2AALDH1A1 | |
| SCHEMBL27524779 | 0.77 | TLR8 (0.62) | TLR8LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL287359 | 0.77 | OXER1 (0.49) | TLR8TRPV1ALDH1A1KDM4E | |
| SCHEMBL26136515 | 0.76 | IKBKB (0.50) | IKBKBTLR8LMNAMEN1NR1I2 | |
| SCHEMBL28162401 | 0.75 | TLR8 (0.69) | TLR8MAPTKMT2AALDH1A1HPGD | |
| Formamide SCHEMBL28501493 | 0.74 | TLR8 (0.62) | TLR8TRPV1ALDH1A1 | |
| SCHEMBL28214718 | 0.74 | TLR8 (0.62) | TLR8MAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103800906-B | For stimulating mammal to the composition of the congenital immunity resistance of pathogen | 德克萨斯大学系统董事会 | 2017-09-22 | — | — | CN | disclosed |
| CN-105126072-A | Compositions for stimulation of mammalian innate immune resistance to pathogens | UNIV TEXAS | 2015-12-09 | — | — | CN | disclosed |
| CN-102439153-B | Compositions for stimulating innate immune resistance to pathogens in mammals | UNIV TEXAS | 2015-07-22 | — | — | CN | disclosed |