SCHEMBL28162401

SCHEMBL28162401

CCCCc1cc2ccccc2nc1CCCC

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 9/20 0.69
PDE10A Q9Y233 1/20 0.44
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GLA P06280 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
ACHE P22303 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168398 0.95 TLR8 (0.69) TLR8ALDH1A1GLAMAPTHPGD
SCHEMBL28214718 0.95 TLR8 (0.62) TLR8PDE10AKMT2AALDH1A1GLA
SCHEMBL28793625 0.93 TLR8 (0.68) TLR8ALDH1A1GLAMAPTHPGD
SCHEMBL27870558 0.93 TLR8 (0.68) TLR8ALDH1A1GLAMAPTHPGD
SCHEMBL28146814 0.92 TLR8 (0.62) TLR8PDE10AKMT2AALDH1A1GLA
Formamide SCHEMBL28501493 0.91 TLR8 (0.62) TLR8PDE10AALDH1A1ATM
SCHEMBL28609423 0.86 TLR8 (0.54) TLR8PDE10AKMT2AALDH1A1GLA
Ammonia Solution, Strong SCHEMBL9131397 0.84 TLR8 (0.53) TLR8PDE10AKMT2AALDH1A1GLA
SCHEMBL1325776 0.84 TLR8 (0.60) TLR8PDE10AKMT2AATM
SCHEMBL1326148 0.84 TLR8 (0.60) TLR8ALDH1A1GLAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103811518-B Photo-electric conversion element, solid camera head and electronic equipment 索尼公司 2017-07-14 CN disclosed