Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28162401 | 0.95 | TLR8 (0.69) | TLR8ATMPDE10AKMT2AALDH1A1 | |
| SCHEMBL28609423 | 0.91 | TLR8 (0.54) | TLR8ATMPDE10AKMT2AALDH1A1 | |
| SCHEMBL168398 | 0.90 | TLR8 (0.69) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL28146814 | 0.90 | TLR8 (0.62) | TLR8ATMPDE10AKMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9131397 | 0.90 | TLR8 (0.53) | TLR8ATMPDE10AKMT2AALDH1A1 | |
| SCHEMBL27870558 | 0.89 | TLR8 (0.68) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL28793625 | 0.89 | TLR8 (0.68) | TLR8ALDH1A1GLAMAPTHPGD | |
| Formamide SCHEMBL28501493 | 0.86 | TLR8 (0.62) | TLR8ATMPDE10AALDH1A1 | |
| SCHEMBL14782918 | 0.83 | TLR8 (0.50) | TLR8ATMPDE10AKMT2AALDH1A1 | |
| Formamide SCHEMBL28779301 | 0.83 | TLR8 (0.50) | TLR8ATMKMT2AALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116263437-A | Structure characterization method of aromatic nitrogen heterocyclic compound in petroleum fraction | 中国石油天然气股份有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-108017579-B | Method for synthesizing quinoline compound by oxidative dehydrogenation of tetrahydroquinoline compound under synergistic catalysis of visible light | 河南大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-108017579-A | A kind of method of visible ray concerted catalysis Tetrahydroquinolinesas oxidative dehydrogenation synthesis of quinoline class compound | 河南大学 | 2018-05-11 | — | — | CN | disclosed |