Toluene

Toluene

SCHEMBL28024170

C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.Cc1ccccc1.Cl[Ni]Cl

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.41
ALOX12 P18054 1/20 0.41
ACHE P22303 1/20 0.41
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.31
HTR1E P28566 1/20 0.31
S1PR3 Q99500 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
CYP3A4 P08684 1/20 0.31
POLB P06746 1/20 0.31
CCR1 P32246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL899669 0.92 TSHR (0.48) TSHRLMNAALOX12ACHEMEN1
Toluene SCHEMBL5492949 0.89 TSHR (0.41) TSHRLMNAALOX12ACHEMEN1
Toluene SCHEMBL5492947 0.89 TSHR (0.44) TSHRLMNAALOX12ACHEMEN1
O-Xylene SCHEMBL16581594 0.78 TSHR (0.46) TSHRLMNAALOX12ACHEMEN1
SCHEMBL10961446 0.77 GAA (0.31)
SCHEMBL11675422 0.77 GAA (0.31)
Toluene SCHEMBL479301 0.76 ACHE (0.52) TSHRLMNAALOX12ACHE
Benzene SCHEMBL9464137 0.74 KDM4E (0.30) MEN1KMT2AALDH1A1KDM4E
SCHEMBL20454582 0.74
SCHEMBL30507734 0.73 ROCK2 (0.40) MEN1KMT2AALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829407-A Method for preparing 2,3-dimethyl-1-butylene through gas-solid phase isomerization catalysis DALIAN CHEMPHY CHEMICAL CO LTD 2015-08-12 CN claimed
CN-104829407-A Method for preparing 2,3-dimethyl-1-butylene through gas-solid phase isomerization catalysis DALIAN CHEMPHY CHEMICAL CO LTD 2015-08-12 CN disclosed