Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950041 | 0.88 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2CYP2C9CYP3A4 | |
| SCHEMBL19191009 | 0.82 | PCSK9 (0.41) | RAB9ANPC1SMN1; SMN2CYP2C9APP | |
| SCHEMBL18365001 | 0.81 | APP (0.52) | RAB9ANPC1SMN1; SMN2CYP2C9CYP3A4 | |
| SCHEMBL19190261 | 0.81 | PCSK9 (0.48) | RAB9ANPC1SMN1; SMN2PCSK9CASP3 | |
| SCHEMBL17840963 | 0.80 | CYP3A4 (0.49) | RAB9ANPC1SMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL19190207 | 0.79 | CYP2C9 (0.42) | RAB9ANPC1SMN1; SMN2CYP2C9CYP3A4 | |
| SCHEMBL17038143 | 0.79 | DYRK1A (0.45) | RAB9ANPC1SMN1; SMN2CYP3A4PCSK9 | |
| SCHEMBL21137709 | 0.78 | CYP3A4 (0.42) | RAB9ANPC1SMN1; SMN2CYP2C9CYP3A4 | |
| SCHEMBL730573 | 0.76 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2CYP2C9CYP3A4 | |
| SCHEMBL12872411 | 0.76 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2APPPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736524-A | Novel compound for imaging Tau protein accumulated in brain | NAT INST RADIOLOG | 2015-06-24 | — | — | CN | disclosed |