Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950041 | 0.80 | RAB9A (0.41) | CYP3A4NPC1RAB9ASMN1; SMN2GSK3B | |
| SCHEMBL18365001 | 0.80 | APP (0.52) | CYP3A4NPC1RAB9ASMN1; SMN2GSK3B | |
| SCHEMBL12336473 | 0.79 | CYP3A4 (0.60) | CYP3A4NPC1RAB9ASMN1; SMN2GSK3B | |
| SCHEMBL19782653 | 0.78 | RAB9A (0.45) | CYP3A4NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL12872411 | 0.78 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2APPTP53 | |
| SCHEMBL28024231 | 0.78 | RAB9A (0.39) | CYP3A4NPC1RAB9ASMN1; SMN2GSK3B | |
| SCHEMBL19190261 | 0.77 | PCSK9 (0.48) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12312877 | 0.77 | CYP3A4 (0.46) | CYP3A4NPC1RAB9ASMN1; SMN2CA2 | |
| SCHEMBL906609 | 0.77 | CYP1A2 (0.59) | CYP3A4NPC1RAB9ASMN1; SMN2APP | |
| SCHEMBL12312848 | 0.76 | CYP3A4 (0.60) | CYP3A4NPC1RAB9ACA2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290784-A1 | LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2019-09-26 | — | — | US | disclosed |
| US-10328161-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10328161-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | GFPT1, QPCT, GLB1 | CYP3A4 759/4885NPC1 3707/4885RAB9A 4461/4885 |
| US-20190290784-A1 | LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF | GFPT1, QPCT, GLB1 | CYP3A4 759/4885NPC1 3707/4885RAB9A 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.