Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211305 | 0.88 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2SCN4AMEN1 | |
| SCHEMBL17840962 | 0.78 | CYP3A4 (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1454367 | 0.76 | APP (0.43) | NPC1RAB9ASMN1; SMN2SCN4AMEN1 | |
| SCHEMBL730573 | 0.76 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2DYRK1AAPP | |
| SCHEMBL12872411 | 0.76 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3901472 | 0.73 | APP (0.56) | MEN1KMT2ADYRK1AAPPCSNK1D | |
| SCHEMBL140656 | 0.72 | HTT (0.56) | DYRK1AAPP | |
| SCHEMBL12312853 | 0.72 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19190176 | 0.72 | APP (0.44) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20681327 | 0.72 | DYRK1A (0.42) | MEN1KMT2ADYRK1AAPPPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736524-A | Novel compound for imaging Tau protein accumulated in brain | NAT INST RADIOLOG | 2015-06-24 | — | — | CN | disclosed |