Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889752 | 1.00 | PKM (0.44) | PKMALDH1A1NCF1CNR2HTT | |
| SCHEMBL4247848 | 0.86 | PKM (0.37) | PKMALDH1A1CNR2RIPK1 | |
| SCHEMBL27311104 | 0.84 | ALDH1A1 (0.42) | PKMALDH1A1NCF1HTTCHRM4 | |
| SCHEMBL14500150 | 0.83 | — | — | |
| SCHEMBL7684250 | 0.83 | — | — | |
| SCHEMBL1661387 | 0.83 | — | — | |
| SCHEMBL3964085 | 0.83 | — | — | |
| SCHEMBL992118 | 0.83 | — | — | |
| SCHEMBL10049272 | 0.83 | — | — | |
| SCHEMBL16838100 | 0.82 | HTT (0.45) | ALDH1A1NCF1HTTRIPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812753-A | Substituted pyridopyrazines as syk inhibitors | HUTCHISON MEDIPHARMA LTD | 2015-07-29 | — | — | CN | disclosed |