Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761874 | 0.91 | MT-CO2 (0.33) | MT-CO2 | |
| SCHEMBL21492702 | 0.81 | ASGR1 (0.30) | ASGR1 | |
| SCHEMBL4144702 | 0.80 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL28827504 | 0.78 | MT-CO2 (0.31) | DGAT1MT-CO2 | |
| SCHEMBL25075599 | 0.78 | HDAC6 (0.33) | DGAT1ASGR1BRD4CREBBPHDAC1 | |
| SCHEMBL28024842 | 0.76 | ASGR1 (0.33) | DGAT1ASGR1HDAC1HDAC2HDAC6 | |
| SCHEMBL30891964 | 0.74 | ASGR1 (0.32) | MT-CO2ASGR1HDAC1HDAC2HDAC6 | |
| SCHEMBL23539177 | 0.74 | ASGR1 (0.32) | ASGR1HDAC1HDAC2HDAC6 | |
| SCHEMBL28132619 | 0.74 | ASGR1 (0.32) | ASGR1HDAC1HDAC2HDAC6 | |
| SCHEMBL3779012 | 0.74 | DGAT1 (0.34) | DGAT1ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755459-A | Fluoromethyl-substituted pyrrolecarboxamides | GRUENENTHAL CHEMIE | 2015-07-01 | — | — | CN | disclosed |