Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28024364 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| Benzene SCHEMBL28022412 | 0.87 | IRAK4 (0.39) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL24436718 | 0.83 | THRB (0.42) | ALDH1A1KCNK3KCNK9TSHRPDK2 | |
| SCHEMBL27860915 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL27051451 | 0.81 | MAPK1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL27040982 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL4128838 | 0.80 | KCNK3 (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL28181802 | 0.80 | AKR1C3 (0.55) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL29042407 | 0.79 | TSHR (0.52) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL1158945 | 0.79 | PRNP (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104800226-A | Applications of O-phenylacetyl-(4-trifluoromethyl) salicylamide compound in preparing drugs used for treating intestinal cancer | HANGZHOU MINSHENG PHARM GROUP | 2015-07-29 | — | — | CN | disclosed |
| CN-104800225-A | Applications of O-phenylacetyl-(4-trifluoromethyl) salicylamide compound in preparing drugs used for treating lung cancer | HANGZHOU MINSHENG PHARM GROUP | 2015-07-29 | — | — | CN | disclosed |