Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644263 | 0.83 | KMT2A (1.00) | KMT2AMAPTSMN1; SMN2GAAUSP2 | |
| SCHEMBL19509566 | 0.82 | KMT2A (0.77) | KMT2AMAPTSMN1; SMN2GAAUSP2 | |
| SCHEMBL14335116 | 0.81 | KDM4E (0.59) | KMT2AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL14055345 | 0.81 | KMT2A (0.59) | KMT2AMAPTKDM4EGAAUSP2 | |
| SCHEMBL19509565 | 0.81 | KMT2A (0.70) | KMT2AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL30721452 | 0.80 | KDM4E (0.68) | KMT2AMAPTKDM4EGAAUSP2 | |
| SCHEMBL6057189 | 0.80 | KDM4E (0.68) | KMT2AMAPTKDM4EGAAUSP2 | |
| SCHEMBL9139340 | 0.79 | KMT2A (0.57) | KMT2AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL6875008 | 0.79 | KMT2A (0.53) | KMT2AKDM4EGAAUSP2ALOX15 | |
| SCHEMBL10664817 | 0.78 | PARP1 (0.58) | KMT2ASMN1; SMN2KDM4EGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041776-A1 | LIPOSOMAL TROPONOID COMPOUND FORMULATIONS | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-03-04 | — | — | WO | disclosed |
| US-20200147086-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | SAINT LOUIS UNIVERSITY (US) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147086-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | DNTT, APRT, RNGTT | KMT2A 804/4885MAPT 3444/4885SMN1; SMN2 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.