Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | YWHAG | P61981 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950528 | 0.86 | MAPT (0.53) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL17774587 | 0.83 | MAPT (0.57) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL17774553 | 0.81 | MAPT (0.59) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL17774624 | 0.81 | MAPT (0.59) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL6797103 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHSD17B10GAA | |
| SCHEMBL28174848 | 0.77 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL6801445 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHSD17B10GAA | |
| SCHEMBL1490844 | 0.74 | KDM4E (0.41) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL30430039 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL26102013 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104804001-B | 4 substituted azoles simultaneously [2,3 d] pyrimidine compound and application thereof | 江苏柯菲平医药股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-104804001-A | 4-substituted pyrrolo [2,3-d]-pyrimidine compound and application thereof | CAREFREE PHARMACEUTICAL CO LTD | 2015-07-29 | — | — | CN | disclosed |