SCHEMBL28025091

SCHEMBL28025091

C=CC(=O)OC(CCN)OC(=O)C=C.[CH2]CCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
GABBR2 O75899 1/20 0.33
GABBR1 Q9UBS5 1/20 0.33
THRB P10828 3/20 0.33
GABRR1 P24046 2/20 0.31
THRA P10827 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3278404 0.89 ALDH1A1 (0.41) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL544590 0.81 TSHR (0.45) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL28025080 0.78 TSHR (0.42) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL9578994 0.78 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4MAPK1
SCHEMBL160397 0.77 TSHR (0.50) TSHRHPGDTHRBTHRA
SCHEMBL8961961 0.77 TSHR (0.41) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL542079 0.75 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL4951003 0.75 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL486802 0.75 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL4578058 0.75 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104812857-A Hydrophilic coating agent OSAKA ORGANIC CHEM IND 2015-07-29 CN disclosed