Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025091 | 0.89 | TSHR (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL3284084 | 0.82 | TSHR (0.40) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL2851825 | 0.80 | TSHR (0.46) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL544590 | 0.78 | TSHR (0.45) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL7766220 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL10430078 | 0.76 | CHRNB2 (0.42) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9578994 | 0.75 | TSHR (0.54) | ALDH1A1CYP3A4MAPK1TSHRHPGD | |
| SCHEMBL13569464 | 0.75 | TSHR (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL4444011 | 0.75 | TSHR (0.41) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL5966667 | 0.75 | TSHR (0.41) | ALDH1A1TP53HIF1ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645297-B1 | Biodegradable absorbent material | KIMBERLY CLARK CO (US) | 2010-06-16 | — | — | EP | claimed |
| CN-1351537-A | Plastic lens systems, compositions and methods | OPTICAL DYNAMICS CORP (US) | 2002-05-29 | — | — | CN | disclosed |