Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719816 | 0.82 | MAPT (0.53) | SYKAURKBINCENPMAOAKDM4E | |
| SCHEMBL15475096 | 0.81 | TUBB1 (0.61) | SYKAURKBINCENPKDM4EALDH1A1 | |
| SCHEMBL26580976 | 0.81 | KDM4E (0.51) | SYKAURKBINCENPMAOAKDM4E | |
| SCHEMBL1073540 | 0.80 | SYK (0.68) | SYKAURKBINCENPKDM4EALDH1A1 | |
| SCHEMBL791890 | 0.80 | FFAR1 (0.61) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL13802180 | 0.80 | MAOB (0.60) | MAOAALDH1A1MAPT | |
| SCHEMBL9719851 | 0.79 | MAOA (0.48) | SYKMAOAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16485526 | 0.79 | PARP10 (0.49) | SYKAURKBINCENPMAOAKDM4E | |
| SCHEMBL20526953 | 0.79 | PARP10 (0.51) | SYKAURKBINCENPMAOAKDM4E | |
| SCHEMBL27299169 | 0.79 | FFAR1 (0.53) | SYKMAOAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903297-A | Novel Pyrazole Derivatives | PHARMA EIGHT CO LTD | 2015-09-09 | — | — | CN | disclosed |