Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539828 | 0.83 | EPHX2 (0.43) | EPHX2NR1H4KCNH2 | |
| SCHEMBL540749 | 0.83 | EPHX2 (0.37) | SETDB1EPHX2NR1H4METAP2 | |
| SCHEMBL27996653 | 0.82 | EPHX2 (0.38) | EPHX2NR1H4CYP3A4CYP2C19FABP3 | |
| SCHEMBL15468119 | 0.82 | TRPV1 (0.38) | EPHX2NR1H4KCNH2 | |
| SCHEMBL793911 | 0.82 | EPHX2 (0.36) | SETDB1EPHX2NR1H4KCNH2METAP2 | |
| SCHEMBL8406404 | 0.81 | MAPT (0.35) | EPHX2NR1H4 | |
| SCHEMBL27989413 | 0.81 | NCF1 (0.37) | — | |
| SCHEMBL795683 | 0.81 | EPHX2 (0.35) | SETDB1EPHX2NR1H4 | |
| SCHEMBL15466458 | 0.79 | P2RX7 (0.35) | SETDB1EPHX2NR1H4KCNH2 | |
| SCHEMBL15466715 | 0.78 | NR1H2 (0.44) | EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483235-B | The aryl pyrrolidines of desinsection | BAYER LANDWIRTSCHAFTLICHE KULTURPFLANZEN SCIENCE AG (DE) | 2015-09-09 | — | — | CN | disclosed |