SCHEMBL28025490

SCHEMBL28025490

Cc1cc(C)c(C)c(C2=C[CH]c3ccccc32)c1C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
XBP1 P17861 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ELANE P08246 1/20 0.33
CYP1A1 P04798 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025445 0.89 KDM4E (0.33) CYP1A2KDM4ECYP3A4MAPTHPGD
SCHEMBL28025516 0.86
SCHEMBL28025437 0.85 TSHR (0.36) CYP1A2CYP3A4ELANECYP1A1
SCHEMBL28025448 0.81 PDK2 (0.37) CYP1A2MAPTHPGDNPSR1
SCHEMBL28025947 0.81 ACHE (0.35) CYP1A2KDM4ECYP3A4MAPTHPGD
SCHEMBL28907130 0.81 MYC (0.39) CYP1A2CYP3A4ELANECYP1A1
SCHEMBL28025456 0.80 KDM4E (0.30) CYP1A2KDM4ECYP3A4MAPTHPGD
SCHEMBL28025999 0.79 MEN1 (0.33) KDM4EMAPTHPGDELANE
SCHEMBL28025439 0.79 PDK2 (0.33) CYP1A2ELANE
SCHEMBL28515390 0.76 NPC1 (0.38) HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed