SCHEMBL28025947

SCHEMBL28025947

Cc1cc(C2=C[CH]c3ccccc32)cc(C)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
XBP1 P17861 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPK1 P28482 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28517482 0.84 HTR7 (0.39) ACHEMAPTNPSR1MEN1KMT2A
SCHEMBL28025423 0.83 BRD9 (0.34) ACHEMAPTMEN1KMT2ALMNA
SCHEMBL28025490 0.81 CYP1A2 (0.34) KDM4EMAPTCYP1A2CYP3A4HPGD
SCHEMBL28302278 0.81 BRD9 (0.33) ACHEMAPTLMNA
SCHEMBL28025456 0.80 KDM4E (0.30) KDM4EMAPTCYP1A2CYP3A4HPGD
SCHEMBL28025439 0.79 PDK2 (0.33) CYP1A2L3MBTL1MAPK1ALDH1A1POLB
SCHEMBL28025445 0.79 KDM4E (0.33) KDM4EMAPTCYP1A2CYP3A4HPGD
SCHEMBL28515419 0.79 NPC1 (0.39) ACHEKDM4EMAPTHPGDNPSR1
SCHEMBL28219408 0.77 ALDH1A1 (0.36) MAPTHPGDXBP1NPSR1MEN1
SCHEMBL28512208 0.76 RAB9A (0.39) ACHEMAPTHPGDNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed