Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27958761 | 0.84 | RXRA (0.43) | RXRARXRBRXRGFADS1KEAP1 | |
| SCHEMBL12543763 | 0.84 | BCAT2 (0.59) | RXRARXRBRXRGFADS1KEAP1 | |
| SCHEMBL27710513 | 0.81 | RPS6KB1 (0.44) | RXRARXRBRXRGFADS1KEAP1 | |
| SCHEMBL6174620 | 0.79 | RXRA (0.44) | RXRARXRBRXRGFADS1KDM4E | |
| SCHEMBL13524581 | 0.78 | RXRA (0.61) | RXRARXRBRXRGPTPN5PARP1 | |
| SCHEMBL11416615 | 0.78 | RXRA (0.61) | RXRARXRBRXRGFADS1PTPN5 | |
| SCHEMBL13246129 | 0.77 | RXRA (0.73) | RXRARXRBRXRGPTPN5 | |
| SCHEMBL10052116 | 0.76 | IKBKB (0.68) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL5074054 | 0.76 | EGFR (0.42) | RXRARXRBRXRGFADS1PARP1 | |
| SCHEMBL6029836 | 0.76 | DHODH (0.51) | RXRARXRBRXRGFADS1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739513-B | 4-methoxyl group-1,3-phenyl-diformyl aminated compounds and application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | claimed |
| CN-103739513-B | 4-methoxyl group-1,3-phenyl-diformyl aminated compounds and application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |
| CN-103739513-B | 4-methoxyl group-1,3-phenyl-diformyl aminated compounds and application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |