Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530803 | 0.95 | ESR1 (0.40) | MBTD1L3MBTL3L3MBTL1FFAR1ESR1 | |
| SCHEMBL11030898 | 0.83 | FFAR1 (0.38) | MBTD1L3MBTL3L3MBTL1FFAR1SLC18A3 | |
| SCHEMBL5037533 | 0.78 | SLC6A2 (0.50) | SLC18A3 | |
| SCHEMBL4070124 | 0.77 | SLC18A3 (0.40) | MBTD1L3MBTL3L3MBTL1SLC18A3MAOA | |
| SCHEMBL11498525 | 0.76 | FFAR1 (0.40) | MBTD1L3MBTL3L3MBTL1FFAR1SLC18A3 | |
| SCHEMBL30228507 | 0.73 | MBTD1 (0.37) | MBTD1L3MBTL3L3MBTL1FFAR1ESR1 | |
| SCHEMBL8646658 | 0.71 | MBTD1 (0.43) | MBTD1L3MBTL3L3MBTL1ESR1ESR2 | |
| SCHEMBL11508468 | 0.70 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL28468815 | 0.70 | FFAR1 (0.41) | MBTD1L3MBTL3L3MBTL1FFAR1SLC18A3 | |
| SCHEMBL8654593 | 0.70 | FFAR1 (0.42) | FFAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796095-B | As the tetrahydroquinoline analogues of muscarinic agonist | ACADIA PHARMACEUTICAL, INC. (US) | 2015-09-09 | — | — | CN | disclosed |