Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 15/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15777319 | 1.00 | KCNH2 (0.36) | KCNH2SLC6A9CNR2CNR1PDE4A | |
| SCHEMBL15776052 | 0.76 | PTGDR2 (0.39) | CNR2 | |
| SCHEMBL15776455 | 0.75 | RORC (0.33) | KCNH2SLC6A9 | |
| SCHEMBL28026359 | 0.75 | RORC (0.33) | KCNH2SLC6A9 | |
| SCHEMBL15777436 | 0.73 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL28026358 | 0.73 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL16115704 | 0.70 | CNR2 (0.40) | CNR2 | |
| SCHEMBL28026344 | 0.65 | GPR84 (0.37) | SLC6A9 | |
| SCHEMBL28026343 | 0.65 | GPR84 (0.37) | SLC6A9 | |
| SCHEMBL15777727 | 0.63 | CNR2 (0.54) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |