Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15776157 | 1.00 | CNR2 (0.43) | CNR2ASPHGABRA1GABRG2GABRB3 | |
| SCHEMBL19225490 | 0.80 | CNR2 (0.65) | CNR2 | |
| SCHEMBL15777540 | 0.80 | CNR2 (0.65) | CNR2 | |
| SCHEMBL15777535 | 0.80 | CNR2 (0.65) | CNR2 | |
| SCHEMBL15776636 | 0.78 | CNR2 (0.60) | CNR2 | |
| SCHEMBL28025786 | 0.78 | CNR2 (0.60) | CNR2 | |
| SCHEMBL19225553 | 0.78 | CNR2 (0.35) | CNR2 | |
| SCHEMBL19225641 | 0.78 | CNR2 (0.58) | CNR2 | |
| SCHEMBL15776347 | 0.77 | CNR2 (0.56) | CNR2 | |
| SCHEMBL15776811 | 0.77 | CNR2 (0.54) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |