Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Alcohol SCHEMBL28583889 | 0.82 | PAM (0.58) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL27887623 | 0.82 | PAM (0.58) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL39220 | 0.82 | PAM (0.58) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL39219 | 0.82 | PAM (0.58) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL4175503 | 0.82 | PAM (0.58) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL891462 | 0.82 | PAM (0.58) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL901221 | 0.81 | PAM (0.52) | PAMHTR2ASIGMAR1ALDH1A1IDO1 | |
| Cinnamic Alcohol SCHEMBL28289701 | 0.81 | PAM (0.52) | PAMHTR2ASIGMAR1ALDH1A1IDO1 | |
| Cinnamic Alcohol SCHEMBL28671092 | 0.80 | PAM (0.56) | PAMHTR2AALDH1A1IDO1CYP3A4 | |
| Cinnamic Alcohol SCHEMBL28671087 | 0.80 | PAM (0.56) | PAMHTR2AALDH1A1IDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803861-B | Method for synthesizing tapentadol hydrochloride | 上海博邦医药科技有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104803861-A | Method for synthesizing tapentadol hydrochloride | SHANGHAI BIOBOND PHARMACEUTICAL CO LTD | 2015-07-29 | — | — | CN | disclosed |