Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27947060 | 0.86 | BIRC2 (0.49) | BIRC2XIAP | |
| Tert-Butyl Formate SCHEMBL27947062 | 0.86 | BIRC2 (0.49) | BIRC2XIAP | |
| SCHEMBL2628596 | 0.76 | BIRC2 (0.36) | BIRC2 | |
| SCHEMBL6100284 | 0.75 | BIRC2 (0.41) | BIRC2 | |
| SCHEMBL28025927 | 0.73 | BIRC2 (0.37) | BIRC2MLNR | |
| SCHEMBL8815561 | 0.72 | BIRC2 (0.40) | BIRC2 | |
| Tert-Butyl Formate SCHEMBL28782248 | 0.72 | TDP1 (0.43) | TDP1 | |
| SCHEMBL24296905 | 0.72 | BIRC2 (0.36) | BIRC2 | |
| SCHEMBL14097349 | 0.72 | BIRC2 (0.41) | BIRC2XIAP | |
| SCHEMBL4960304 | 0.71 | BIRC2 (0.35) | BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492376-B | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LTD | 2015-07-22 | — | — | CN | disclosed |