Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815561 | 0.97 | BIRC2 (0.40) | BIRC2MAPTHSD17B10ITGB3ITGB2 | |
| SCHEMBL15894887 | 0.89 | BIRC2 (0.38) | BIRC2MAPTHSD17B10ITGB3ITGB2 | |
| SCHEMBL24296905 | 0.86 | BIRC2 (0.36) | BIRC2MAPTHSD17B10 | |
| SCHEMBL14097349 | 0.86 | BIRC2 (0.41) | BIRC2MAPTHSD17B10GRIN2DGRIN3B | |
| SCHEMBL6865237 | 0.85 | HSD17B10 (0.35) | BIRC2HSD17B10ITGB3ITGB2ITGB1 | |
| SCHEMBL31679369 | 0.83 | CXCR4 (0.42) | BIRC2HSD17B10ITGB3ITGB2ITGB1 | |
| SCHEMBL9187015 | 0.83 | BIRC2 (0.40) | BIRC2MAPTHSD17B10GRIN2DGRIN3B | |
| SCHEMBL2628596 | 0.81 | BIRC2 (0.36) | BIRC2MAPTHSD17B10GRIN2DGRIN3B | |
| SCHEMBL1468944 | 0.79 | BIRC2 (0.35) | BIRC2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4960304 | 0.79 | BIRC2 (0.35) | BIRC2MAPTITGB3ITGB2ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668973-B2 | Components for producing amphoteric liposomes | MARINA BIOTECH, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20140227345-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | MARINA BIOTECH, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-7109326-B2 | Halo-alkoxycarbonyl prodrugs | GENENTECH, INC. (US) | 2006-09-19 | — | — | US | disclosed |
| EP-0975608-B1 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040220401-A1 | Novel halo-alkoxycarbonyl prodrugs | GENENTECH, INC. | 2004-11-04 | — | — | US | disclosed |
| US-20010020019-A1 | NOVEL HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH, INC. | 2001-09-06 | — | — | US | disclosed |
| EP-0975608-A2 | HALO-ALKOXYCARBONYL PRODRUGS | Genentech, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046576-A2 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH, INC. (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220401-A1 | Novel halo-alkoxycarbonyl prodrugs | PNP, PAICS, PHOSPHO1 | BIRC2 3234/4885MAPT 2386/4885HSD17B10 1050/4885 |
| US-20140227345-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | PHOSPHO1, SGMS1, CHMP4B | BIRC2 357/4885MAPT 3179/4885HSD17B10 3084/4885 |
| US-20010020019-A1 | NOVEL HALO-ALKOXYCARBONYL PRODRUGS | PNP, PAICS, PHOSPHO1 | BIRC2 3234/4885MAPT 2386/4885HSD17B10 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.