SCHEMBL2628596

SCHEMBL2628596

O=COCC1CN(CC(=O)O)CCN1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BIRC2 Q13490 1/20 0.36
LTA4H P09960 1/20 0.34
MAPT P10636 1/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.31
GRIN2D O15399 2/20 0.31
GRIN3B O60391 2/20 0.31
THRB P10828 2/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2A Q12879 2/20 0.31
GRIN2B Q13224 2/20 0.31
GRIN2C Q14957 2/20 0.31
GRIN3A Q8TCU5 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6100284 0.81 BIRC2 (0.41) BIRC2MAPTALOX15HSD17B10GRIN2D
SCHEMBL8815561 0.78 BIRC2 (0.40) BIRC2MAPTALOX15HSD17B10GRIN2D
SCHEMBL14097349 0.78 BIRC2 (0.41) BIRC2MAPTALOX15HSD17B10GRIN2D
Tert-Butyl Formate SCHEMBL28025928 0.76 BIRC2 (0.35) BIRC2
SCHEMBL9187015 0.75 BIRC2 (0.40) BIRC2MAPTALOX15HSD17B10GRIN2D
SCHEMBL15894887 0.72 BIRC2 (0.38) BIRC2MAPTALOX15HSD17B10GRIN2D
SCHEMBL2628598 0.72 BCHE (0.38)
SCHEMBL28026498 0.71 MAPT (0.45) BIRC2MAPTALOX15HSD17B10GRIN2D
SCHEMBL2628597 0.71 HSD17B10 (0.41) HSD17B10
Tert-Butyl Formate SCHEMBL27947062 0.70 BIRC2 (0.49) BIRC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580297-B2 Components for producing amphoteric liposomes MARINA BIOTECH, INC. (US) 2013-11-12 US disclosed
US-20120100205-A1 COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES MARINA BIOTECH, INC. 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100205-A1 COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES PHOSPHO1, SGMS1, CHMP4B BIRC2 357/4885LTA4H 175/4885MAPT 3179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.